Across TCGA cell cohorts, OTUD6A mutation is significantly associated with the mutation status of many other genes, with 2,387 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OTUD6A-associated genes across cancer lineages are TANC1, MAP4K4, and XPO1. Each is linked with OTUD6A in more than 2 cancer types. Because this analysis shows association rather than direction, both OTUD6A-to-partner and partner-to-OTUD6A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUD6A→partner) and Y-score (partner→OTUD6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TANC1 →	+4.187	+5.000	.008	.008	1	3
LUNG_NSCLC_LUAD	MAP4K4 →	+4.187	+5.000	.008	.008	1	3
BLOOD_Leukemia	XPO1 →	+4.321	+5.285	.005	.005	1	3
LARGE_INTESTINE	RB1CC1 →	+2.471	+2.584	.001	.001	1	3
LARGE_INTESTINE	RIMBP2 →	+1.693	+2.287	.005	.005	1	3
BLOOD_Lymphoma	PLXNA2 →	+3.169	+4.601	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,387 associations by consensus.

Exploration

OTUD6A survival (RNA) · tumor vs normal (RNA) · all OTUD6A data types