OTUD4

Across TCGA patient cohorts, OTUD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,164 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible OTUD4-associated GO terms across cancer lineages are Positive regulation of chromosome organization, Nuclear-transcribed mRNA catabolic process, and Autophagosome maturation. Each is linked with OTUD4 in more than 33 cancer types. Because this analysis shows association rather than direction, both OTUD4-to-partner and partner-to-OTUD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome organization grouped by OTUD4-low versus OTUD4-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUD4→partner) and Y-score (partner→OTUD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of chromosome organization →	+0.065	+1.385	<.001	<.001	3	34
DLBC	Nuclear-transcribed mRNA catabolic process →	+0.071	+1.414	<.001	<.001	3	34
SCLC	Autophagosome maturation →	+0.084	+1.100	<.001	<.001	3	34
THYM	Hormone-mediated signaling pathway →	+0.059	+1.355	<.001	<.001	3	34
DLBC	Post-embryonic development →	+0.067	+1.441	<.001	<.001	3	34
DLBC	Centriole assembly →	+0.077	+1.436	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,164 associations by consensus.

Positive regulation of chromosome organization by OTUD4 expression — DLBC

Explore this box plot interactively →