OTUD3

Across TCGA cell cohorts, OTUD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,858 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OTUD3-associated GO terms across cancer lineages are Microtubule organizing center organization, Negative regulation of cell cycle process, and Cell cycle checkpoint signaling. Each is linked with OTUD3 in more than 18 cancer types. Because this analysis shows association rather than direction, both OTUD3-to-partner and partner-to-OTUD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by OTUD3-low versus OTUD3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUD3→partner) and Y-score (partner→OTUD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule organizing center organization →	+0.098	+1.524	<.001	<.001	3	19
SOFT_TISSUE	Negative regulation of cell cycle process →	+0.068	+1.450	<.001	<.001	3	18
BONE	Cell cycle checkpoint signaling →	+0.089	+1.212	<.001	<.001	3	18
BLOOD_Myeloma	Positive regulation of organelle assembly →	+0.070	+0.700	<.001	.001	3	17
STOMACH	Protein K27-linked deubiquitination →	+0.138	+1.128	<.001	<.001	1	19
BREAST	Regulation of chromosome organization →	+0.085	+0.890	.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,858 associations by consensus.

Microtubule organizing center organization by OTUD3 expression — LARGE_INTESTINE

Explore this box plot interactively →