OTUB2

Across TCGA patient cohorts, OTUB2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,506 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible OTUB2-associated genes across cancer lineages are GEN1, TRAJ30, and RNU6-678P. Each is linked with OTUB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OTUB2-to-partner and partner-to-OTUB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OTUB2 versus GEN1 in HNSC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUB2→partner) and Y-score (partner→OTUB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GEN1 →	-0.627	-0.691	<.001	.001	3	2
UCEC	TRAJ30 →	-1.933	-0.540	.001	.003	3	2
UCEC	RNU6-678P →	-1.305	-0.493	<.001	.009	3	2
GBM	DDX3P2 →	-1.923	-0.533	.007	.005	3	2
GBM	ZNF141 →	-0.643	-0.506	.005	.007	2	3
GBM	HDHD2 →	-1.030	-0.533	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,506 associations by consensus.

OTUB2 vs GEN1 — HNSC

Explore this scatter interactively →