OTUB1

Across TCGA patient cohorts, OTUB1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,971 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OTUB1-associated genes across cancer lineages are PRDX5, RTN3, and TRMT112. Each is linked with OTUB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both OTUB1-to-partner and partner-to-OTUB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OTUB1 versus PRDX5 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTUB1→partner) and Y-score (partner→OTUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PRDX5 →	+0.622	+0.258	.002	.002	3	6
LSCC	RTN3 →	+0.567	+0.252	<.001	<.001	3	5
LSCC	TRMT112 →	+0.592	+0.268	<.001	<.001	3	5
UCEC	COX8A →	+1.044	+0.164	.002	.002	3	5
UCEC	TMEM179B →	+0.483	+0.114	.001	.001	3	5
BRCA	TKFC →	+0.593	+0.326	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,971 associations by consensus.

OTUB1 vs PRDX5 — OV

Explore this scatter interactively →