OTP

Across TCGA patient cohorts, OTP RNA expression is significantly associated with the protein abundance of many other proteins, with 7,897 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OTP-associated proteins across cancer lineages are DEPTOR, KDM3A, and WDR12. Each is linked with OTP in more than 2 cancer types. Because this analysis shows association rather than direction, both OTP-to-partner and partner-to-OTP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OTP versus DEPTOR in GBM, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OTP→partner) and Y-score (partner→OTP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DEPTOR →	-0.408	-0.729	<.001	<.001	3	3
LSCC	KDM3A →	+0.511	+0.073	<.001	<.001	3	3
GBM	WDR12 →	+0.381	+0.994	<.001	<.001	3	3
LSCC	AQR →	+0.316	+0.086	<.001	<.001	3	3
LSCC	SNRNP200 →	+0.213	+0.077	<.001	.001	3	3
BRCA	TNS2 →	-0.288	-0.096	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,897 associations by consensus.

OTP vs DEPTOR — GBM

Explore this scatter interactively →