OTOL1

Across TCGA patient cohorts, OTOL1 protein abundance is significantly associated with the RNA expression of many other genes, with 557 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible OTOL1-associated genes across cancer lineages are KHNYN, PRMT5, and ITPK1. Each is linked with OTOL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OTOL1-to-partner and partner-to-OTOL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OTOL1 versus KHNYN in CCRCC, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTOL1→partner) and Y-score (partner→OTOL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KHNYN →	-0.486	-0.675	.003	<.001	3	1
CCRCC	PRMT5 →	-0.797	-0.695	.009	.008	3	1
CCRCC	ITPK1 →	-0.634	-0.561	.005	.006	3	1
CCRCC	C14orf93 →	-0.762	-0.615	.005	.002	3	1
CCRCC	RABGGTA →	-0.418	-0.675	<.001	<.001	3	1
CCRCC	CSTF1 →	-0.386	-0.674	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 557 associations by consensus.

OTOL1 vs KHNYN — CCRCC

Explore this scatter interactively →