Across TCGA patient cohorts, OST4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,462 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OST4-associated proteins across cancer lineages are BIRC6, YWHAQ, and P4HA1. Each is linked with OST4 in more than 4 cancer types. Because this analysis shows association rather than direction, both OST4-to-partner and partner-to-OST4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OST4→partner) and Y-score (partner→OST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	BIRC6 →	+0.213	+0.512	.001	.003	3	5
LSCC	YWHAQ →	+0.313	+0.393	<.001	<.001	3	4
CCRCC	P4HA1 →	+0.595	+0.275	<.001	<.001	3	4
HNSC	UTP3 →	+0.330	+1.050	<.001	.006	3	4
LSCC	PSME4 →	+0.292	+0.383	.002	.001	3	4
COAD	CHDH →	-0.415	-0.239	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,462 associations by consensus.

Exploration

OST4 survival (RNA) · tumor vs normal (RNA) · all OST4 data types