OSGEPL1-AS1

Across TCGA pan-cancer cohorts, OSGEPL1-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated OSGEPL1-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher OSGEPL1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OSGEPL1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and PAAD show a favorable association.

ACC, BLCA, and PAAD are the cancer types where OSGEPL1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.195	0.646	<.001	102	view →
BLCA	DFS	Tertile	III,IV	0.510	0.354	.001	81	view →
PAAD	OS	Median	All	0.529	0.256	<.001	56	view →
READ	OS	Median	II,III,IV	0.942	0.486	.004	47	view →
UVM	OS	Median	III,IV	0.296	1.000	.005	41	view →
KIRP	DFS	Median	II,III,IV	0.928	0.176	<.001	32	view →
KIRC	DFS	Median	II,III,IV	0.448	0.594	.010	28	view →
LIHC	DFS	Quartile	All	0.450	0.613	.008	28	view →
LGG	DFS	Tertile	All	0.774	0.876	.001	24	view →
OV	DFS	Quartile	IV	0.660	0.403	.025	18	view →
CHOL	DFS	Tertile	All	0.595	0.099	.004	15	view →
DLBC	OS	Quartile	II,III,IV	0.209	0.797	.008	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

OSGEPL1-AS1–ACC (DFS)

Open the ACC breakdown →