OSGEPL1-AS1

Across TCGA pan-cancer cohorts, OSGEPL1-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of OSGEPL1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where OSGEPL1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types OSGEPL1-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, COAD, and THCA are the cancer types where OSGEPL1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OSGEPL1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.251	<.001	10	view →
COAD	Male	All	+0.349	<.001	10	view →
THCA	All	All	−0.235	<.001	9	view →
LIHC	All	II,III,IV	+0.337	<.001	8	view →
KIRC	Male	All	−0.245	<.001	8	view →
BRCA	Female	II,III,IV	−0.172	.006	6	view →
CHOL	Male	All	+1.145	<.001	5	view →
STAD	All	II,III,IV	+0.377	.001	4	view →
READ	Female	All	+0.662	<.001	3	view →
LUAD	Female	II,III,IV	−0.525	.001	3	view →
BLCA	Female	III,IV	+0.397	.016	2	view →
ESCA	Female	All	−0.396	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

OSGEPL1-AS1–KICH

Open the KICH breakdown →