OSCP1

Across TCGA patient cohorts, OSCP1 mutation is significantly associated with the RNA expression of many other genes, with 593 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OSCP1-associated genes across cancer lineages are MIR3663, KRT8P6, and RPL17P12. Each is linked with OSCP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OSCP1-to-partner and partner-to-OSCP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3663 grouped by OSCP1-low versus OSCP1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSCP1→partner) and Y-score (partner→OSCP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR3663 →	+0.279	+5.137	<.001	.002	3	3
COAD	KRT8P6 →	+0.119	+3.569	<.001	.004	3	3
LUSC	RPL17P12 →	+0.649	+5.569	<.001	<.001	3	3
CESC	LINC01568 →	+0.017	+4.653	<.001	.004	3	2
BRCA	KRTAP21-1 →	+0.147	+3.733	<.001	.004	3	2
BRCA	UBE2V1P4 →	+0.072	+4.811	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 593 associations by consensus.

MIR3663 by OSCP1 expression — BRCA

Explore this box plot interactively →