OSCP1

Across TCGA pan-cancer cohorts, OSCP1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of OSCP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where OSCP1 RNA is repressed in tumor relative to normal tissue. In most cancer types OSCP1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and LUAD are the cancer types where OSCP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OSCP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−2.218	<.001	11	view →
THCA	All	IV	−1.212	<.001	11	view →
LUAD	Male	II,III,IV	−1.001	<.001	9	view →
LUSC	Male	II,III,IV	−1.386	<.001	8	view →
KIRC	Male	II,III,IV	−0.477	<.001	8	view →
LIHC	All	All	+0.409	<.001	4	view →
COAD	All	All	+0.332	.005	4	view →
CHOL	All	All	+2.334	<.001	3	view →
UCEC	All	All	−0.594	.048	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

OSCP1–KICH

Open the KICH breakdown →