OSCP1

Across TCGA cell cohorts, OSCP1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OSCP1-associated genes across cancer lineages are ACER1, IQCF6, and PRAMEF19. Each is linked with OSCP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OSCP1-to-partner and partner-to-OSCP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by OSCP1-low versus OSCP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSCP1→partner) and Y-score (partner→OSCP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.072	+3.145	.006	.004	3	1
LARGE_INTESTINE	IQCF6 →	+0.188	+3.297	<.001	.002	3	1
BREAST	PRAMEF19 →	+0.019	+5.169	<.001	.005	3	1
LARGE_INTESTINE	SH3GL2 →	+1.603	+3.252	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ACER1 by OSCP1 expression — LARGE_INTESTINE

Explore this box plot interactively →