OSBPL9

Across TCGA pan-cancer cohorts, OSBPL9 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated OSBPL9 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher OSBPL9 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated OSBPL9 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, GBM, and PDAC are the cancer types where OSBPL9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	1.000	0.926	.003	32	view →
GBM	OS	Median	All	0.393	0.655	<.001	28	view →
PDAC	OS	Tertile	All	0.410	0.624	.016	20	view →
HNSC	DFS	Quartile	II,III,IV	0.949	0.695	.004	16	view →
UCEC	OS	Tertile	II,III,IV	0.603	1.000	.027	8	view →
CCRCC	OS	Median	IV	0.451	1.000	.016	4	view →
LSCC	DFS	Median	II,III,IV	0.852	0.689	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

OSBPL9–LUAD (OS)

Open the LUAD breakdown →