OSBPL9

Across TCGA patient cohorts, OSBPL9 mutation is significantly associated with the RNA expression of many other genes, with 4,365 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OSBPL9-associated genes across cancer lineages are COX15, GFM2, and GLOD4. Each is linked with OSBPL9 in more than 2 cancer types. Because this analysis shows association rather than direction, both OSBPL9-to-partner and partner-to-OSBPL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX15 grouped by OSBPL9-low versus OSBPL9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL9→partner) and Y-score (partner→OSBPL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COX15 →	+0.520	+2.536	<.001	<.001	3	3
UCEC	GFM2 →	+0.635	+3.257	<.001	<.001	3	3
UCEC	GLOD4 →	+0.544	+2.546	<.001	<.001	3	3
UCEC	NUDT9 →	+0.388	+4.169	<.001	<.001	3	3
KIRC	MIR4478 →	+0.395	+5.038	<.001	.009	3	3
UCEC	LARP1B →	+0.566	+2.589	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,365 associations by consensus.

COX15 by OSBPL9 expression — UCEC

Explore this box plot interactively →