OSBPL8

Across TCGA patient cohorts, OSBPL8 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,662 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible OSBPL8-associated proteins across cancer lineages are PPP1R12A, ARL3, and PHLDB2. Each is linked with OSBPL8 in more than 3 cancer types. Because this analysis shows association rather than direction, both OSBPL8-to-partner and partner-to-OSBPL8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSBPL8 versus PPP1R12A in COAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL8→partner) and Y-score (partner→OSBPL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PPP1R12A →	+0.255	+0.573	<.001	<.001	3	4
BRCA	ARL3 →	+0.376	+0.715	.001	.003	3	4
UCEC	PHLDB2 →	+0.414	+0.569	.001	<.001	3	4
BRCA	SPON1 →	+0.650	+0.777	.001	.001	3	4
COAD	TBRG4 →	-0.395	-0.542	<.001	<.001	3	4
BRCA	TFB2M →	-0.512	-1.009	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,662 associations by consensus.

OSBPL8 vs PPP1R12A — COAD

Explore this scatter interactively →