OSBPL8

Across TCGA cell cohorts, OSBPL8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,912 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OSBPL8-associated GO terms across cancer lineages are Adiponectin-activated signaling pathway, Positive regulation of gluconeogenesis, and Positive regulation of pinocytosis. Each is linked with OSBPL8 in more than 12 cancer types. Because this analysis shows association rather than direction, both OSBPL8-to-partner and partner-to-OSBPL8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adiponectin-activated signaling pathway grouped by OSBPL8-low versus OSBPL8-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL8→partner) and Y-score (partner→OSBPL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Adiponectin-activated signaling pathway →	+0.151	+0.926	<.001	.004	3	13
URINARY_TRACT	Positive regulation of gluconeogenesis →	+0.139	+0.724	.001	.003	3	13
BLOOD_Leukemia	Positive regulation of pinocytosis →	+0.128	+0.779	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Regulation of hippo signaling →	+0.104	+0.992	.001	<.001	3	13
BREAST	Negative regulation of bicellular tight junction assembly →	+0.126	+0.722	.001	.001	3	13
OVARY	Interkinetic nuclear migration →	+0.079	+0.727	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,912 associations by consensus.

Adiponectin-activated signaling pathway by OSBPL8 expression — KIDNEY

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