OSBPL7

Across TCGA patient cohorts, OSBPL7 protein abundance is significantly associated with the RNA expression of many other genes, with 11,779 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OSBPL7-associated genes across cancer lineages are NCAPH, CHEK2, and PARPBP. Each is linked with OSBPL7 in more than 5 cancer types. Because this analysis shows association rather than direction, both OSBPL7-to-partner and partner-to-OSBPL7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSBPL7 versus NCAPH in BRCA, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL7→partner) and Y-score (partner→OSBPL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NCAPH →	-0.830	-0.304	<.001	<.001	3	6
LSCC	CHEK2 →	-0.665	-0.202	<.001	<.001	3	6
LSCC	PARPBP →	-0.718	-0.267	<.001	<.001	3	6
UCEC	GTSE1 →	-1.060	-0.332	<.001	<.001	3	6
UCEC	TPX2 →	-1.115	-0.271	<.001	.002	3	6
UCEC	FANCA →	-0.854	-0.346	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,779 associations by consensus.

OSBPL7 vs NCAPH — BRCA

Explore this scatter interactively →