OSBPL7

Across TCGA patient cohorts, OSBPL7 mutation is significantly associated with the RNA expression of many other genes, with 1,382 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OSBPL7-associated genes across cancer lineages are REG1CP, MIR7845, and MTND5P4. Each is linked with OSBPL7 in more than 2 cancer types. Because this analysis shows association rather than direction, both OSBPL7-to-partner and partner-to-OSBPL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG1CP grouped by OSBPL7-low versus OSBPL7-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL7→partner) and Y-score (partner→OSBPL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	REG1CP →	+0.208	+2.363	.001	.003	3	3
SKCM	MIR7845 →	+0.219	+2.186	<.001	.009	3	3
UCEC	MTND5P4 →	+0.229	+1.634	.002	.004	3	2
UCEC	TXN2 →	+0.292	+2.035	.003	<.001	3	2
UCEC	IL2RB →	+0.619	+3.470	.008	.002	3	2
UCEC	RSPO4 →	-0.976	-2.252	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,382 associations by consensus.

REG1CP by OSBPL7 expression — COAD

Explore this box plot interactively →