OSBPL6

Across TCGA patient cohorts, OSBPL6 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,430 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OSBPL6-associated proteins across cancer lineages are OSBPL6_S190, OSBPL6_S290, and OSBPL6_S344. Each is linked with OSBPL6 in more than 7 cancer types. Because this analysis shows association rather than direction, both OSBPL6-to-partner and partner-to-OSBPL6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSBPL6 versus OSBPL6_S190 in UCEC, with a Pearson correlation of 0.85.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL6→partner) and Y-score (partner→OSBPL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OSBPL6_S190 →	+1.236	+1.736	<.001	<.001	3	8
BRCA	OSBPL6_S290 →	+1.493	+1.514	<.001	<.001	3	7
LSCC	OSBPL6_S344 →	+0.950	+0.996	<.001	<.001	3	7
UCEC	OSBPL6_S44 →	+0.872	+1.361	<.001	<.001	3	6
UCEC	OSBPL6_S9 →	+2.929	+4.678	.006	<.001	3	5
OV	PPFIBP2_S387 →	-0.686	-0.559	.002	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,430 associations by consensus.

OSBPL6 vs OSBPL6_S190 — UCEC

Explore this scatter interactively →