OSBPL6

Across TCGA patient cohorts, OSBPL6 protein abundance is significantly associated with the RNA expression of many other genes, with 14,059 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OSBPL6-associated genes across cancer lineages are COLGALT2, NPNT, and REEP1. Each is linked with OSBPL6 in more than 4 cancer types. Because this analysis shows association rather than direction, both OSBPL6-to-partner and partner-to-OSBPL6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSBPL6 versus COLGALT2 in LSCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL6→partner) and Y-score (partner→OSBPL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	COLGALT2 →	+0.917	+0.278	<.001	<.001	3	5
BRCA	NPNT →	+1.664	+0.436	<.001	.003	3	4
BRCA	REEP1 →	+1.621	+0.632	<.001	<.001	3	4
GBM	FAT3 →	+0.779	+0.193	.003	.004	3	4
BRCA	CST4 →	+1.249	+0.503	.002	<.001	3	3
BRCA	LFNG →	+1.236	+0.533	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,059 associations by consensus.

OSBPL6 vs COLGALT2 — LSCC

Explore this scatter interactively →