OSBPL6

Across TCGA cell cohorts, OSBPL6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,479 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OSBPL6-associated GO terms across cancer lineages are DNA-templated transcription initiation, Olfactory bulb interneuron development, and Ribose phosphate biosynthetic process. Each is linked with OSBPL6 in more than 11 cancer types. Because this analysis shows association rather than direction, both OSBPL6-to-partner and partner-to-OSBPL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by OSBPL6-low versus OSBPL6-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL6→partner) and Y-score (partner→OSBPL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	DNA-templated transcription initiation →	+0.072	+2.105	<.001	<.001	3	12
STOMACH	Olfactory bulb interneuron development →	+1.430	+1.802	<.001	<.001	3	12
SKIN	Ribose phosphate biosynthetic process →	+0.072	+1.270	<.001	.001	3	12
STOMACH	Negative regulation of post-translational protein modification →	+0.090	+2.069	<.001	<.001	3	11
SKIN	Regulation of cytokinesis →	+0.069	+1.234	<.001	<.001	3	11
BLOOD_Lymphoma	Vesicle cargo loading →	+0.069	+1.273	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,479 associations by consensus.

DNA-templated transcription initiation by OSBPL6 expression — STOMACH

Explore this box plot interactively →