OSBPL5

Across TCGA patient cohorts, OSBPL5 protein abundance is significantly associated with the RNA expression of many other genes, with 15,124 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OSBPL5-associated genes across cancer lineages are SEC24D, HTRA1, and CERCAM. Each is linked with OSBPL5 in more than 4 cancer types. Because this analysis shows association rather than direction, both OSBPL5-to-partner and partner-to-OSBPL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSBPL5 versus SEC24D in OV, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL5→partner) and Y-score (partner→OSBPL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SEC24D →	+0.782	+0.370	.001	.001	3	5
BRCA	HTRA1 →	+0.960	+0.234	.001	.001	3	5
OV	CERCAM →	+0.859	+0.435	<.001	<.001	3	5
OV	PDGFRL →	+1.284	+0.390	<.001	<.001	3	4
UCEC	EDA2R →	+0.937	+0.278	.001	.002	3	4
OV	NT5E →	+1.251	+0.268	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,124 associations by consensus.

OSBPL5 vs SEC24D — OV

Explore this scatter interactively →