OSBPL5

Across TCGA cell cohorts, OSBPL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,633 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OSBPL5-associated GO terms across cancer lineages are Phosphatidylserine acyl-chain remodeling, Methylglyoxal catabolic process, and Actin filament depolymerization. Each is linked with OSBPL5 in more than 10 cancer types. Because this analysis shows association rather than direction, both OSBPL5-to-partner and partner-to-OSBPL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylserine acyl-chain remodeling grouped by OSBPL5-low versus OSBPL5-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL5→partner) and Y-score (partner→OSBPL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Phosphatidylserine acyl-chain remodeling →	+0.184	+1.278	<.001	<.001	3	11
OESOPHAGUS	Methylglyoxal catabolic process →	+0.172	+1.087	.003	.002	3	11
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.207	+1.358	.003	.007	3	10
BONE	Vesicle-mediated transport to the plasma membrane →	+0.086	+1.422	<.001	.001	2	11
BONE	Phospholipid transport →	+0.052	+1.267	.001	<.001	3	10
SOFT_TISSUE	Endosomal transport →	+0.053	+1.003	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,633 associations by consensus.

Phosphatidylserine acyl-chain remodeling by OSBPL5 expression — PANCREAS

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