OSBPL11

Across TCGA cell cohorts, OSBPL11 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,061 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OSBPL11-associated GO terms across cancer lineages are Protein localization to chromosome, Regulation of RNA export from nucleus, and Sister chromatid cohesion. Each is linked with OSBPL11 in more than 15 cancer types. Because this analysis shows association rather than direction, both OSBPL11-to-partner and partner-to-OSBPL11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome grouped by OSBPL11-low versus OSBPL11-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL11→partner) and Y-score (partner→OSBPL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein localization to chromosome →	+0.086	+0.655	.001	.001	3	16
LUNG_SCLC	Regulation of RNA export from nucleus →	+0.134	+0.472	<.001	.006	3	16
BLOOD_Lymphoma	Sister chromatid cohesion →	+0.104	+1.172	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Double-strand break repair via nonhomologous end joining →	+0.073	+0.788	.001	.001	3	16
SOFT_TISSUE	Regulation of chromosome condensation →	+0.213	+0.660	<.001	.003	3	16
PANCREAS	Regulation of chromosome separation →	+0.167	+0.879	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,061 associations by consensus.

Protein localization to chromosome by OSBPL11 expression — LUNG_SCLC

Explore this box plot interactively →