OSBPL10

Across TCGA patient cohorts, OSBPL10 protein abundance is significantly associated with the RNA expression of many other genes, with 11,197 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OSBPL10-associated genes across cancer lineages are ZNF860, ZNF587P1, and OSBPL10-AS1. Each is linked with OSBPL10 in more than 7 cancer types. Because this analysis shows association rather than direction, both OSBPL10-to-partner and partner-to-OSBPL10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSBPL10 versus ZNF860 in BRCA, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL10→partner) and Y-score (partner→OSBPL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF860 →	+1.102	+0.591	<.001	<.001	3	8
UCEC	ZNF587P1 →	+0.859	+0.368	<.001	<.001	3	7
GBM	OSBPL10-AS1 →	+0.639	+0.391	<.001	<.001	3	7
BRCA	TAF5 →	-0.514	-0.534	<.001	.001	3	4
HNSC	ALG3 →	-0.740	-0.367	.001	<.001	3	4
GBM	MEOX2 →	+1.486	+0.198	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,197 associations by consensus.

OSBPL10 vs ZNF860 — BRCA

Explore this scatter interactively →