OSBPL10

Across TCGA cell cohorts, OSBPL10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,989 significant associations in total. BONE shows the largest number of these associations.

The most reproducible OSBPL10-associated GO terms across cancer lineages are Phospholipid transfer to membrane, Regulation of cardiac muscle hypertrophy, and Rho protein signal transduction. Each is linked with OSBPL10 in more than 12 cancer types. Because this analysis shows association rather than direction, both OSBPL10-to-partner and partner-to-OSBPL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phospholipid transfer to membrane grouped by OSBPL10-low versus OSBPL10-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL10→partner) and Y-score (partner→OSBPL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Phospholipid transfer to membrane →	+0.148	+1.343	<.001	<.001	3	13
BONE	Regulation of cardiac muscle hypertrophy →	+0.127	+2.314	.001	.004	3	12
LARGE_INTESTINE	Rho protein signal transduction →	+0.107	+1.047	<.001	.004	3	11
BONE	Regulation of intracellular transport →	+0.075	+2.529	<.001	.001	3	11
OVARY	Negative regulation of protein-containing complex disassembly →	+0.085	+1.571	<.001	.002	3	11
BREAST	Intermembrane lipid transfer →	+0.095	+1.238	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,989 associations by consensus.

Phospholipid transfer to membrane by OSBPL10 expression — OVARY

Explore this box plot interactively →