OSBPL10-AS1

Across TCGA pan-cancer cohorts, OSBPL10-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated OSBPL10-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher OSBPL10-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OSBPL10-AS1 expression acts as an unfavorable survival marker, although some lineages such as CHOL and SKCM show a favorable association.

KIRC, MESO, and CESC are the cancer types where OSBPL10-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	II,III,IV	0.418	0.607	<.001	123	view →
MESO	DFS	Median	IV	0.162	0.454	.001	38	view →
CESC	DFS	Quartile	II,III,IV	0.312	0.669	.002	38	view →
LIHC	OS	Quartile	III,IV	0.409	0.687	.001	36	view →
UCEC	OS	Tertile	IV	0.191	0.714	.003	26	view →
CHOL	DFS	Tertile	III,IV	0.779	0.178	.017	15	view →
PAAD	DFS	Tertile	II,III,IV	0.251	0.368	.016	13	view →
ACC	DFS	Quartile	All	0.319	0.629	.007	13	view →
SKCM	DFS	Median	All	0.261	0.160	.005	10	view →
UCS	OS	Quartile	All	0.785	0.463	.022	10	view →
ESCA	DFS	Tertile	All	0.658	1.000	.049	9	view →
PCPG	DFS	Tertile	All	0.652	0.895	.036	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

OSBPL10-AS1–KIRC (DFS)

Open the KIRC breakdown →