OSBPL10-AS1

Across TCGA pan-cancer cohorts, OSBPL10-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of OSBPL10-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where OSBPL10-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types OSBPL10-AS1 is over-expressed in tumor, although a few such as HNSC and UCEC show the opposite, repressed pattern.

HNSC, STAD, and COAD are the cancer types where OSBPL10-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OSBPL10-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	II,III,IV	−0.046	.013	5	view →
STAD	Male	All	+0.084	.014	4	view →
COAD	Female	All	+0.045	.029	3	view →
THCA	Male	All	+0.032	.011	3	view →
ESCA	All	II,III,IV	+0.150	.035	2	view →
UCEC	All	IV	−0.135	.037	2	view →
KICH	Male	III,IV	−0.047	.010	2	view →
READ	All	All	+0.047	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

OSBPL10-AS1–HNSC

Open the HNSC breakdown →