Across TCGA patient cohorts, ORM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,818 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ORM2-associated proteins across cancer lineages are BIN2_S462, FMNL1, and APOBR. Each is linked with ORM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ORM2-to-partner and partner-to-ORM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ORM2→partner) and Y-score (partner→ORM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BIN2_S462 →	+0.676	+0.455	<.001	.006	3	5
LSCC	FMNL1 →	+0.405	+0.746	<.001	<.001	3	4
LSCC	APOBR →	+0.407	+0.932	<.001	<.001	3	4
OV	NECAP2 →	+0.187	+0.488	.006	.004	3	4
HNSC	ARHGAP25 →	+0.558	+0.570	<.001	<.001	3	4
HNSC	INPP5D →	+0.519	+0.554	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,818 associations by consensus.

Exploration

ORM2 survival (RNA) · tumor vs normal (RNA) · all ORM2 data types