Across TCGA patient cohorts, ORM2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,839 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ORM2-associated genes across cancer lineages are AOC3, LYVE1, and ADGRL4. Each is linked with ORM2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ORM2-to-partner and partner-to-ORM2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ORM2→partner) and Y-score (partner→ORM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AOC3 →	+1.161	+0.528	<.001	<.001	3	7
GBM	LYVE1 →	+1.442	+0.598	<.001	<.001	3	7
CCRCC	ADGRL4 →	+0.748	+0.537	<.001	.002	3	7
CCRCC	LOXHD1 →	+0.552	+0.483	<.001	.005	3	7
GBM	F13A1 →	+2.106	+0.670	<.001	<.001	3	6
OV	IGFBP4 →	+1.427	+0.834	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,839 associations by consensus.

Exploration

ORM2 survival (RNA) · tumor vs normal (RNA) · all ORM2 data types