ORM2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ORM2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ORM2-associated genes across cancer lineages are OLIG3 and ELOA3DP. Each is linked with ORM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ORM2-to-partner and partner-to-ORM2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ORM2→partner) and Y-score (partner→ORM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOLIG3 →+0.024+4.095.008.00931
LARGE_INTESTINEELOA3DP →+0.023+4.273.003.00631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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