OR9K2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR9K2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR9K2-associated genes across cancer lineages are GALNTL5, ODF1, and AVPR1B. Each is linked with OR9K2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR9K2-to-partner and partner-to-OR9K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALNTL5 grouped by OR9K2-low versus OR9K2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR9K2→partner) and Y-score (partner→OR9K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINGALNTL5 →+0.021+4.415<.001.00731
SKINODF1 →+0.020+5.022<.001.00231
SKINAVPR1B →+0.009+4.415<.001.00731
LUNG_NSCLC_LUADCCDC42 →+0.062+3.688<.001.00231
LUNG_NSCLC_LUADDRD5 →+0.403+3.343<.001.00531
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GALNTL5 by OR9K2 expression — SKIN

Box plot of GALNTL5 in OR9K2-low vs OR9K2-high samples in SKIN.

Explore this box plot interactively →

Exploration