OR9I1

Across TCGA patient cohorts, OR9I1 mutation is significantly associated with the RNA expression of many other genes, with 944 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR9I1-associated genes across cancer lineages are RNU6-159P, FAM177A1, and ATMIN. Each is linked with OR9I1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR9I1-to-partner and partner-to-OR9I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-159P grouped by OR9I1-low versus OR9I1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR9I1→partner) and Y-score (partner→OR9I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-159P →	+0.274	+7.954	<.001	.008	3	2
UCEC	FAM177A1 →	+0.515	+3.716	<.001	<.001	3	2
UCEC	ATMIN →	+0.537	+2.447	<.001	.001	3	2
UCEC	KATNAL2 →	-0.872	-3.055	<.001	<.001	3	2
LUSC	KARS1 →	+0.454	+3.471	.001	.002	3	2
UCEC	ACTN1 →	+0.531	+3.354	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 944 associations by consensus.

RNU6-159P by OR9I1 expression — HNSC

Explore this box plot interactively →