OR8U1

Across TCGA patient cohorts, OR8U1 mutation is significantly associated with the RNA expression of many other genes, with 1,417 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8U1-associated genes across cancer lineages are DNAJA1P1, GUF1, and EME1. Each is linked with OR8U1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8U1-to-partner and partner-to-OR8U1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAJA1P1 grouped by OR8U1-low versus OR8U1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8U1→partner) and Y-score (partner→OR8U1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	DNAJA1P1 →	+0.057	+5.306	<.001	.006	3	2
UCEC	GUF1 →	+0.496	+3.010	.001	<.001	3	2
UCEC	EME1 →	+0.884	+3.743	<.001	<.001	3	2
UCEC	MRPL17 →	+0.442	+3.724	<.001	<.001	3	2
UCEC	TONSL →	+0.764	+2.343	<.001	.003	3	2
UCEC	RECQL4 →	+0.972	+3.700	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,417 associations by consensus.

DNAJA1P1 by OR8U1 expression — CESC

Explore this box plot interactively →