OR8U1

Across TCGA cell cohorts, OR8U1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR8U1-associated genes across cancer lineages are ACER1, TAAR8, and ODF1. Each is linked with OR8U1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8U1-to-partner and partner-to-OR8U1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by OR8U1-low versus OR8U1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8U1→partner) and Y-score (partner→OR8U1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.098	+3.823	.001	.006	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.013	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	ODF1 →	+0.062	+4.093	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR52E2 →	+0.238	+4.472	<.001	.001	3	1
LUNG_NSCLC_LUAD	MS4A13 →	+0.130	+4.813	<.001	<.001	3	1
LUNG_NSCLC_LUAD	PATE3 →	+0.062	+3.745	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ACER1 by OR8U1 expression — LARGE_INTESTINE

Explore this box plot interactively →