OR8K3

Across TCGA cell cohorts, OR8K3 RNA expression is significantly associated with the mutation status of many other genes, with 127 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OR8K3-associated genes across cancer lineages are PCDHGB4, PDZRN4, and NFIC. Each is linked with OR8K3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8K3-to-partner and partner-to-OR8K3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCDHGB4 grouped by OR8K3-low versus OR8K3-high in URINARY_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8K3→partner) and Y-score (partner→OR8K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	PCDHGB4 →	+5.087	+0.033	.004	<.001	3	2
BREAST	PDZRN4 →	+4.196	+0.065	.006	<.001	3	2
LUNG_NSCLC_LUAD	NFIC →	+4.681	+0.004	.003	<.001	3	2
LUNG_SCLC	OSBPL10 →	+5.029	+0.016	.006	<.001	3	2
CNS	ZNF618 →	+4.169	+0.007	.008	<.001	3	2
CNS	DNAJC13 →	+5.754	+0.013	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 127 associations by consensus.

PCDHGB4 by OR8K3 expression — URINARY_TRACT

Explore this box plot interactively →