OR8J1

Across TCGA patient cohorts, OR8J1 mutation is significantly associated with the RNA expression of many other genes, with 2,779 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8J1-associated genes across cancer lineages are PTPRG-AS1, BLOC1S3, and E2F1. Each is linked with OR8J1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR8J1-to-partner and partner-to-OR8J1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTPRG-AS1 grouped by OR8J1-low versus OR8J1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8J1→partner) and Y-score (partner→OR8J1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PTPRG-AS1 →	+0.436	+2.713	.001	.003	3	3
UCEC	BLOC1S3 →	+0.393	+2.169	<.001	<.001	3	3
UCEC	E2F1 →	+0.840	+2.534	<.001	<.001	3	3
READ	ANKRD33B-AS1 →	+0.187	+6.681	<.001	<.001	3	2
LIHC	NMS →	+0.125	+6.479	<.001	.001	3	2
LIHC	RN7SL310P →	+0.164	+5.355	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,779 associations by consensus.

PTPRG-AS1 by OR8J1 expression — SKCM

Explore this box plot interactively →