OR8J1

Across TCGA cell cohorts, OR8J1 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR8J1-associated genes across cancer lineages are OR8B8, OR14K1, and IQCF5. Each is linked with OR8J1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8J1-to-partner and partner-to-OR8J1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B8 grouped by OR8J1-low versus OR8J1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8J1→partner) and Y-score (partner→OR8J1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR8B8 →	+0.029	+5.149	<.001	<.001	3	2
LARGE_INTESTINE	OR14K1 →	+0.068	+4.022	<.001	.006	3	1
LARGE_INTESTINE	IQCF5 →	+0.025	+4.022	<.001	.006	3	1
LARGE_INTESTINE	KCNU1 →	+0.041	+3.345	.001	.007	3	1
LARGE_INTESTINE	TBX5 →	+0.242	+3.626	.001	.006	3	1
CNS	OR1E2 →	+0.431	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

OR8B8 by OR8J1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →