OR8I2

Across TCGA patient cohorts, OR8I2 mutation is significantly associated with the RNA expression of many other genes, with 1,089 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8I2-associated genes across cancer lineages are RNU6-618P, NPIPA8, and ACKR4P1. Each is linked with OR8I2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR8I2-to-partner and partner-to-OR8I2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-618P grouped by OR8I2-low versus OR8I2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8I2→partner) and Y-score (partner→OR8I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-618P →	+0.269	+4.014	.001	.004	3	2
LIHC	NPIPA8 →	+0.039	+4.261	.002	.003	3	2
LIHC	ACKR4P1 →	+0.069	+3.868	<.001	.006	3	2
BLCA	MIR4733 →	+0.746	+5.305	<.001	<.001	3	2
UCEC	ACD →	+0.497	+3.721	<.001	<.001	3	2
UCEC	UFSP2 →	+0.537	+2.042	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,089 associations by consensus.

RNU6-618P by OR8I2 expression — LIHC

Explore this box plot interactively →