OR8H1

Across TCGA cell cohorts, OR8H1 mutation is significantly associated with the RNA expression of many other genes, with 133 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR8H1-associated genes across cancer lineages are IL27, KCTD17, and MYL12A. Each is linked with OR8H1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8H1-to-partner and partner-to-OR8H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL27 grouped by OR8H1-low versus OR8H1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8H1→partner) and Y-score (partner→OR8H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	IL27 →	+0.058	+4.315	<.001	.006	3	1
SKIN	KCTD17 →	-1.011	-3.278	<.001	.006	3	1
SKIN	MYL12A →	+0.635	+3.067	.001	.009	3	1
SKIN	MED26 →	-0.427	-3.278	.001	.006	3	1
SKIN	CLCN6 →	-0.711	-3.278	.001	.006	3	1
SKIN	CEP72 →	-0.682	-3.278	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

IL27 by OR8H1 expression — CNS

Explore this box plot interactively →