OR8G5

Across TCGA patient cohorts, OR8G5 mutation is significantly associated with the RNA expression of many other genes, with 1,621 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8G5-associated genes across cancer lineages are PUS3, NARS1, and CEP78. Each is linked with OR8G5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR8G5-to-partner and partner-to-OR8G5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PUS3 grouped by OR8G5-low versus OR8G5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8G5→partner) and Y-score (partner→OR8G5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PUS3 →	+0.432	+2.622	.005	.005	3	3
SKCM	NARS1 →	+0.440	+3.546	.005	.002	3	3
SKCM	CEP78 →	+0.434	+3.459	.008	.005	3	3
UCEC	LONP1 →	+0.651	+3.491	<.001	.002	3	3
SKCM	MYPOP →	+0.357	+2.521	.001	.001	3	3
UCEC	EMC8 →	+0.473	+2.364	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,621 associations by consensus.

PUS3 by OR8G5 expression — SKCM

Explore this box plot interactively →