OR8G5

Across TCGA pan-cancer cohorts, OR8G5 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR8G5’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where OR8G5 RNA is repressed in tumor relative to normal tissue. In most cancer types OR8G5 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

COAD, KIRP, and THCA are the cancer types where OR8G5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR8G5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	−0.115	<.001	10	view →
KIRP	All	II,III,IV	+0.045	.012	5	view →
THCA	All	All	+0.081	<.001	4	view →
LIHC	All	All	+0.207	.005	2	view →
READ	All	All	−0.123	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

OR8G5–COAD

Open the COAD breakdown →