OR8G5

Across TCGA cell cohorts, OR8G5 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR8G5-associated genes across cancer lineages are C4orf50, SERPINB12, and QRFPR. Each is linked with OR8G5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8G5-to-partner and partner-to-OR8G5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C4orf50 grouped by OR8G5-low versus OR8G5-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8G5→partner) and Y-score (partner→OR8G5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C4orf50 →	+0.020	+4.684	<.001	.002	3	1
LARGE_INTESTINE	SERPINB12 →	+0.141	+3.823	<.001	.006	3	1
LARGE_INTESTINE	QRFPR →	+1.393	+3.854	<.001	.006	3	1
LARGE_INTESTINE	OR6Q1 →	+0.018	+4.437	<.001	.004	3	1
CNS	IL31 →	+0.045	+4.981	<.001	.008	3	1
LUNG_NSCLC_LUAD	TGM7 →	+0.006	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

C4orf50 by OR8G5 expression — SKIN

Explore this box plot interactively →