OR8G5

Across TCGA cell cohorts, OR8G5 mutation is significantly associated with the mutation status of many other genes, with 1,199 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR8G5-associated genes across cancer lineages are FAM186A, ENTHD1, and ZNF777. Each is linked with OR8G5 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR8G5-to-partner and partner-to-OR8G5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM186A grouped by OR8G5-low versus OR8G5-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8G5→partner) and Y-score (partner→OR8G5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FAM186A →	+3.053	+3.718	.006	.006	1	4
LARGE_INTESTINE	ENTHD1 →	+2.936	+4.471	.001	.001	1	4
BREAST	ZNF777 →	+5.297	+5.297	.004	.004	1	3
LUNG_NSCLC_LUAD	GIMAP8 →	+4.772	+5.339	.004	.004	1	3
LUNG_NSCLC_LUAD	ATG2A →	+4.187	+5.000	.008	.008	1	3
LUNG_NSCLC_LUAD	CHST9 →	+4.772	+5.339	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,199 associations by consensus.

FAM186A by OR8G5 expression — SKIN

Explore this box plot interactively →