Across TCGA patient cohorts, OR8D1 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8D1-associated genes across cancer lineages are PEA-15_pS116, EGFR, and Paxillin. Each is linked with OR8D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8D1-to-partner and partner-to-OR8D1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8D1→partner) and Y-score (partner→OR8D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PEA-15_pS116 →	+0.296	+2.816	.041	.036	3	1
UCEC	EGFR →	-0.178	-2.321	.027	.035	3	1
UCEC	Paxillin →	+0.284	+3.459	.029	.005	3	1
UCEC	PDCD4 →	-0.701	-2.321	.002	.035	3	1
UCEC	Tuberin →	+0.462	+3.179	<.001	.010	3	1
SKCM	Acetyl-a-Tubulin-Lys40 →	+0.391	+1.874	.048	.047	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

OR8D1 survival (RNA) · tumor vs normal (RNA) · all OR8D1 data types