Across TCGA cell cohorts, OR8D1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR8D1-associated genes across cancer lineages are CRX, MS4A4A, and ZNF831. Each is linked with OR8D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8D1-to-partner and partner-to-OR8D1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8D1→partner) and Y-score (partner→OR8D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CRX →	+0.005	+3.930	<.001	.003	3	1
LARGE_INTESTINE	MS4A4A →	+0.176	+3.000	<.001	.006	3	1
LARGE_INTESTINE	ZNF831 →	+0.011	+3.103	<.001	.004	3	1
LARGE_INTESTINE	VSIG4 →	+0.023	+3.376	<.001	.002	3	1
LARGE_INTESTINE	TAFA1 →	+0.239	+3.103	.001	.004	3	1
LARGE_INTESTINE	KRTAP5-3 →	+0.037	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

OR8D1 survival (RNA) · tumor vs normal (RNA) · all OR8D1 data types