Across TCGA patient cohorts, OR8B8 mutation is significantly associated with the RNA expression of many other genes, with 1,159 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8B8-associated genes across cancer lineages are GTF2IP6, DGKZ, and SAR1B. Each is linked with OR8B8 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8B8-to-partner and partner-to-OR8B8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8B8→partner) and Y-score (partner→OR8B8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	GTF2IP6 →	+1.464	+4.378	<.001	.006	3	2
UCEC	DGKZ →	+0.421	+3.711	<.001	<.001	3	2
UCEC	SAR1B →	+0.383	+2.246	.008	.005	3	2
UCEC	CENPH →	+0.719	+2.098	<.001	.003	3	2
UCEC	SEC13 →	+0.430	+3.491	<.001	.002	3	2
UCEC	ABR →	+0.539	+3.459	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,159 associations by consensus.

Exploration

OR8B8 survival (RNA) · tumor vs normal (RNA) · all OR8B8 data types