Across TCGA pan-cancer cohorts, OR8B8 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated OR8B8 data layer compared with 7 for mutation status.
The strongest signal is observed in stomach adenocarcinoma (STAD), where higher OR8B8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR8B8 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.
STAD, SCLC, and DLBC are the cancer types where OR8B8 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.