OR8B12

Across TCGA patient cohorts, OR8B12 mutation is significantly associated with the RNA expression of many other genes, with 1,465 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR8B12-associated genes across cancer lineages are OR10H5, SDHA, and CPLX3. Each is linked with OR8B12 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR8B12-to-partner and partner-to-OR8B12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10H5 grouped by OR8B12-low versus OR8B12-high in SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8B12→partner) and Y-score (partner→OR8B12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	OR10H5 →	+0.076	+4.039	<.001	.009	3	3
LUAD	SDHA →	+0.494	+3.368	.002	.004	3	3
LUSC	CPLX3 →	+0.008	+4.102	<.001	.007	3	3
SKCM	CDRT4 →	-0.173	-2.636	.002	.005	3	3
COAD	RN7SL551P →	+0.414	+5.790	.002	.003	3	2
COAD	RNU6-1089P →	+0.643	+5.435	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,465 associations by consensus.

OR10H5 by OR8B12 expression — SCLC

Explore this box plot interactively →